Name | (3beta,5xi,16alpha)-3,16-dihydroxy-24-methylidenelanosta-7,9(11)-dien-21-oic acid |
Synonyms | deydrotumulosic acid dehydrotumulosic acid 3β,16α-Dihydroxy-24-methylenelanosta-7,9(11)-dien-21-oic acid 3β,16α-Dihydroxy-24-methylene-5α-lanosta-7,9(11)-dien-21-oic acid (3beta,16alpha)-3,16-Dihydroxy-24-methylenelanosta-7,9(11)-dien-21-oic acid (3beta,5xi,16alpha)-3,16-dihydroxy-24-methylidenelanosta-7,9(11)-dien-21-oic acid |
CAS | 6754-16-1 |
InChI | InChI=1/C31H48O4/c1-18(2)19(3)9-10-20(27(34)35)26-23(32)17-31(8)22-11-12-24-28(4,5)25(33)14-15-29(24,6)21(22)13-16-30(26,31)7/h11,13,18,20,23-26,32-33H,3,9-10,12,14-17H2,1-2,4-8H3,(H,34,35)/t20-,23-,24?,25+,26+,29-,30-,31+/m1/s1 |
Molecular Formula | C31H48O4 |
Molar Mass | 484.71 |
Density | 1.11±0.1 g/cm3(Predicted) |
Melting Point | 272-275℃ |
Boling Point | 621.7±55.0 °C(Predicted) |
Flash Point | 343.8°C |
Vapor Presure | 4.65E-18mmHg at 25°C |
Appearance | Powder |
pKa | 4.63±0.10(Predicted) |
Storage Condition | 2-8℃ |
Refractive Index | 1.56 |
Physical and Chemical Properties | Soluble in methanol, ethanol, DMSO and other organic solvents, derived from poria cocos. |
Reference Show more | 1. Wu Wen Wu Rui Feng Kang Jiang Li. Study on the fingerprint and content determination of Shenling Jianwu powder [J]. China pharmacist 2019 22(05):852-856. 2. Zhao qiulong, bianxiaokun, Qian Dawei, Shulan, Guo Sheng, Wang Tuanfeng, Duan Jinyu. Metabolites of Guizhi Fuling capsule in plasma, bile, urine and feces of primary dysmenorrhea model rats [J]. Journal of Pharmaceutical Analysis, 2021,41(01):51-63. 3. [IF = 3.512] Binbin Wang et al."Comprehensive Quality Assessment of Kaixin Powder by HPLC-DAD Quantification and HPLC-QTOF-MS/MS Confirmation. Acs Omega. 2021;6(17):11319-11326 |
biological activity | Dehydrotumulosic acid is a dehydrogluconic acid isolated from chloroform-soluble matter of Ethanol extracts of fungi, it is one of the effective components of poria cocos. Poria cocos is a popular source of Chinese herbal fungi, with pharmacological uses for diuresis, excretion of moisture, strengthening the spleen and tranquilizing mind, and regulating the body's immune system. |
Use | for content determination/identification/pharmacological experiments. |